General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology

Voorkant
Howard L. Kaufman, Jedd D. Wolchok
Springer Science & Business Media, 12 okt 2007 - 503 pagina's

"General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.

 

Inhoudsopgave

Tumor Antigens
17
T Cells and Antigen Recognition 33
32
The Role of Natural Killer T Cells in Tumor Immunity
55
Immunomodulatory Molecules of the Immune System
67
HLA Class I Antigen Abnormalities in Tumors 123
122
The Local Tumor Microenvironment
145
Peptide and Protein Vaccines for Cancer 171
169
DNA Vaccines Against Cancer
193
Whole Cell Vaccines
275
Carbohydrate Vaccines Against Cancer 297
296
Monoclonal Antibody Therapy of Cancer 321
319
Adoptive Cellular Therapy for the Treatment of Cancer
343
Checkpoint Blockade and Combinatorial Immunotherapies
363
General Approaches to Measuring Immune Responses 393
392
High Dose Interleukin2 Therapy
431
Monoclonal Antibodies in Cancer Therapy
453

Recombinant Viral and Bacterial Vaccines
217
Dendritic Cell Vaccines
251

Overige edities - Alles bekijken

Veelvoorkomende woorden en zinsdelen

Populaire passages

Pagina 13 - Carswell, EA, Old, LJ, Kassel, RL, Green, S., Fiore, N., and Williamson, B. 1975. An endotoxininduced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 72:3666-3670.
Pagina 13 - Vaccinae, a Disease discovered in some of the Western Counties of England, particularly Gloucestershire, and known by the Name of Cow-pox.
Pagina 498 - Dudley, ME, Wunderlich, JR, Robbins, PF, Yang, JC, Hwu, P., Schwartzentruber, DJ, Topalian, SL, Sherry, R., Restifo, NP, Hubicki, AM, Robinson, MR, Raffeld, M., Duray, P., Seipp, CA, Rogers-Freezer, L., Morton, KE, Mavroukakis, SA, White, DE, and Rosenberg, SA (2002).

Bibliografische gegevens