Cancer - Between Glycolysis and Physical Constraint: Between Glycolysis and Physical ConstraintSpringer Science & Business Media, 22 mrt 2004 - 150 pagina's Considerable effort has gone into the research of common cancers - lung, bowel, ovarian, cervical, and prostate cancer. In recent years, however, there has been a lack of breakthroughs in therapeutic advances. By challenging many established beliefs, Cancer explores these issues by offering new perspectives on the study of cancer and exploring the areas of mathematics, physics and chemistry in cancer research. This book is for cancer specialists, clinicians, and researchers interested in an innovative view in cancer research. |
Inhoudsopgave
Introduction | 1 |
Are Cancer Cells Malignant Per Se? | 15 |
Cell Growth A Balance Between Glycolysis and Physical Constraint | 23 |
Extracellular Constraints Regulate Cell Differentiation | 29 |
Changes in Cellular Constraints During Carcinogenesis | 43 |
Hypoxia Is Responsible for Changes in Cellular Constraints During Inflammation | 51 |
Fibrosis Perpetuates Hypoxia | 63 |
Metastasis The Hunt for Food | 71 |
Epidemiology Aging as the Main Cause of Cancer | 87 |
Aging Causes Inflammation and Fibrosis Mimicking the Impact of Carcinogens | 95 |
Inhibition of Metabolism Slows Aging and Decreases Cancer Incidence | 101 |
A Complication of Hypoxia The Loss of Cell Polarity Explains Cancer Cell Proliferation | 107 |
The Loss of Cell Differentiation Is a Consequence of Glycolysis | 117 |
Response to Treatment A Balance Between Glycolysis and Physical Constraints | 123 |
Targeting Glycolysis | 135 |
Conclusion | 145 |
Overige edities - Alles bekijken
Cancer - Between Glycolysis and Physical Constraint Laurent Schwartz Geen voorbeeld beschikbaar - 2011 |
Veelvoorkomende woorden en zinsdelen
2-deoxy-D-glucose anaerobic glycolysis animal anomalies architectural bacteria Biol biphosphonates bone breast cancer Caloric restriction cancer cells cancer incidence carcinogenesis carcinogens carcinoma cardiac cartilage causes cell differentiation cell division cell polarity cell respiration cellular changes CHAPTER chemical chemotherapy chondrocytes chronic cirrhosis Clin clinical collagen consequence culture cytokines cytotoxic death decrease disease effect epithelial cells epithelium extracellular matrix extracellular matrix deposition fibroblasts fibrosis fractal function gap junction gastric gene genetic genome glucose growth factors growth plate hepatocarcinoma hormones human cells hypothesis hypoxia hypoxia-inducible hypoxic increased induce inflammation inhibition lactic acid liver loss of cell lung cancer malignant mechanical stress metabolism metastasis mice mitochondrial molecular molecules mortality muscle mutations normal cells oncogene organ ossification osteoclast oxygen patients Petri dish physical constraints Physiol proteins radiation rats responsible risk role secretion shear stress Similarly skin target tendon tion treatment tumor cells tumor growth vascular vitro vivo Warburg
Populaire passages
Pagina 121 - Fluorine-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients. Eur J Nucl Med 23: 1409-1415 297.