Comprehensive Organic Transformations, 4 Volume Set: A Guide to Functional Group Preparations

Voorkant
PROSE Award Finalist 2019 - Multivolume Reference/Science Association of American Publishers Award for Professional and Scholarly Excellence

PROSE Award Finalist 2019 - Multivolume Reference/Science

Association of American Publishers Award for Professional and Scholarly Excellence

This greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations.

  • Covers and cross references so practicing chemists can easily navigate through the book’s comprehensive coverage of reagents and reactions
  • Updates and expands a best-selling guide through the year 2011

"...the book is undoubtedly still of great value and every chemist working in the area of synthesis should have it within reach in the laboratory."
Angewandte Chemie review of the 2nd edition

"...an indispensable reference work for designing and carrying out modern organic chemical synthesis.... It is amazing that so much information is contained in a single volume that is arranged in a logical and easy to use fashion."
Analytical Biochemistry review of the 2nd edition

 

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Inhoudsopgave

LITERATURE ABBREVIATIONS
xxxix
CHEMICAL ABBREVIATIONS
xlix
1
5
Alkynes
110
11
137
12
147
Sulfur Compounds
158
12
168
FROM NITRO COMPOUNDS
1605
HETEROATOM AND METAL SUBSTITUTION
1617
FROM ALDEHYDES KETONES AND DERIVATIVES
1631
17
1638
19
1657
20
1667
23
1673
25
1680

13
179
14
180
17
182
18
183
COUPLING REACTIONS
193
FRIEDELCRAFTS AND RELATED ALKYLATION REACTIONS
343
RINGFORMING REACTIONS
355
5
443
AROMATIZATION
467
GENERAL REFERENCES
521
Contents 2 ELIMINATION
571
Dehydrohalogenation and Elimination of Alkyl Halides
577
11Dihalides
580
12Dihalides
581
13Dihalides
585
Trihaloalkanes
586
Halohydrins
589
Halo Aldehydes and Ketones
590
Halo Carboxylic Acids
591
βHalo Sulfonates
592
Amines
593
Quaternary Ammonium Salts
594
Diazo Compounds
595
βSubstituted Azides
596
βSubstituted Ethers
603
Sulfides
604
αHalosulfides
605
βHydroxysulfides
606
βAlkoxy and HydroxySulfoxides
607
Sulfones
608
αHalosulfones RambergBšcklund Reaction
609
βHydroxysulfones
610
βAcyloxysulfones
611
Other βSubstituted Sulfones
612
Disulfones
613
Selenoxides
614
Tellurides
617
βOxysilanes and Stannanes
618
Sulfonate Esters
622
Sulfates
623
Xanthates
624
Carbamates
625
3
645
4
661
5
693
Contents
706
6
711
8
722
10
729
19
734
21
735
22
736
23
737
24
742
25
754
6
767
DIENES AND POLYENES
879
Contents
998
DIELSALDER REACTIONS 1017
xxiv
ALKYNES 1143
xxv
xxvi
xxvi
Contents
xxviii
Contents
xxx
xxxii
xxxii
Contents
xxxiv
Contents
xxxviii
LITERATURE ABBREVIATIONS XXXIX
xxxix
GENERAL REFERENCES
1145
ISOMERIZATION AND METATHESIS
1147
Metathesis
1149
ELIMINATION REACTIONS
1151
WITTIG AND RELATED APPROACHES
1169
ALKYLATION ALKENYLATION AND ARYLATION OF ALKYNES AND ALLENES 1 Organolithium Sodium and Magnesium Compounds
1175
Organoboron Compounds
1182
Organoaluminum Compounds
1185
Organogallium Compounds
1187
Organoindium Compounds
1188
Organothallium Compounds
1189
Organotin Compounds
1191
Organotellurium Compounds
1195
Organozirconium Compounds
1196
Organochromium Compounds
1197
Organoiron Compounds
1198
Organoruthenium Compounds
1199
Organocobalt Compounds
1200
Organorhodium Compounds
1202
Organopalladium Compounds
1204
Organocopper Compounds
1214
Organosilver Compounds
1223
Organozinc Compounds
1225
Organomercury Compounds
1227
Organolutetium Compounds
1228
HALIDES
1231
GENERAL REFERENCES
1233
HALOGENATION OF HYDROCARBONS
1237
32
1238
Allylic Halogenation
1241
Benzylic Halogenation
1243
35
1247
HALOGENATION OF ALKENES AND DIENES
1269
4
1313
5
1333
6
1345
7
1355
8
1361
9
1385
11
1397
1175
1419
12
1459
13
1467
14
1481
FROM ARENES
1487
15
1500
16
1514
FROM ALKYL AND ARYL HALIDES OR SULFONATES
1529
FROM OTHER AMINES AND DERIVATIVES
1545
FROM AZIDES
1595
FROM CARBOXYLIC ACIDS AND DERIVATIVES
1697
FROM NITRILES
1709
Ultracentrifugation 1028
xxiv
1617
xxvii
19
xxx
Organoaluminum Gallium Indium and Thallium
xxxvi
LITERATURE ABBREVIATIONS XXXIX
xxxix
GENERAL REFERENCES
1719
ALKYLATION OF ALCOHOLS PHENOLS AND DERIVATIVES
1743
ALKANE ARENE ALKENE AND ALKYNE SUBSTITUTIONS AND ADDITIONS
1859
5
1963
4
2053
GENERAL REFERENCES
2059
ALCOHOL TRANSPOSITION
2067
OXIDATION
2083
ALKENE DIENE AND ALKYNE ADDITIONS
2107
ORGANOBORANES
2143
ETHER CLEAVAGE
2163
REDUCTION
2269
ALKYLATION OF CARBONYL COMPOUNDS
2339
MISCELLANEOUS REACTIONS
2437
Contents
xvii
ALDEHYDES AND KETONES 2439
xviii
GENERAL REFERENCES
2441
OXIDATION
2449
3
2469
5
2470
REDUCTION OF PHENOLS CARBOXYLIC ACIDS AND DERIVATIVES
2587
Anhydrides
2593
7
2596
REARRANGEMENTS
2605
CONDENSATION REACTIONS
2687
Dieckmann and Related Reactions
2693
CYCLIZATION AND ANNULATION REACTIONS
2721
CARBONYLATION AND RELATED REACTIONS
2783
ELECTROPHILIC ACYLATION
2831
NUCLEOPHILIC ACYLATION
2927
SULFUR SELENIUM AND TELLURIUM REAGENTS
2949
HETEROCYCLES
2961
CARBONYL HOMOLOGATION
2969
ALKYLATION AND ACYLATION OF ALDEHYDES KETONES
2981
ALKYLATION OF αAND βSUBSTITUTED CARBONYL COMPOUNDS
3127
AND DERIVATIVES
3141
Compounds
3192
Organosilicon Compounds
3194
Organogermanium Compounds
3198
Organolead Compounds
3200
Organozirconium Compounds
3201
Organomanganese Compounds
3202
Organoruthenium Compounds
3203
Organocobalt Compounds
3204
Organorhodium Compounds
3205
Organonickel Compounds
3207
Organopalladium Compounds
3211
Organocopper Compounds
3213
Organosilver Compounds
3234
Organozinc Compounds
3235
Organomercury Compounds
3237
Organosamarium Compounds
3238
NITRILES CARBOXYLIC ACIDS AND DERIVATIVES
3243
GENERAL REFERENCES
3245
OXIDATION SUBSTITUTION AND ADDITION
3247
Arenes
3250
Alkenes
3252
Dienes
3262
Alkynes
3263
Alkyl Halides
3268
Amines
3269
Imines and Derivatives
3272
Nitrothioalkenes
3273
Sulfides
3279
Diols
3286
Amino Alcohols
3289
Azido Alcohols
3290
Ketones
3308
Hemiacetals and Lactols
3321
Acetals
3322
Carboxylic Acids
3324
REDUCTION
3331
CARBONYL HOMOLOGATION AND DEGRADATION
3399
ALKYLATION ACYLATION AND SUBSTITUTION OF NITRILES
3409
REARRANGEMENTS
3619
Ring Opening
3643
Ring Expansion
3644
DecarboxylationAllylation
3645
LACTONE AND LACTAM FORMATION
3647
INTERCONVERSION OF NITRILES CARBOXYLIC ACIDS AND DERIVATIVES
3749
Carboxylic Acids to Acid Anhydrides
3751
Carboxylic Acids to Esters
3753
Carboxylic Acids to Amides
3764
Carboxylic Acids to Imides
3775
Carboxylic Acids to Nitriles
3776
Acid Halides to Acid Anhydrides
3777
Acid Halides to Esters
3778
Acid Halides to Amides
3781
Acid Halides to Imides
3782
Acid Anhydrides to Acid Halides
3783
Acid Anhydrides to Amides
3787
Acid Anhydrides to Imides
3788
Esters to Carboxylic Acids
3789
Esters to Acid Halides
3798
Esters to Acid Anhydrides
3799
Esters to Amides
3805
Esters to Nitriles
3808
Amides to Carboxylic Acids
3809
Amides to Esters
3810
Amides to Other Amides
3811
Amides to Imides
3816
Amides to Nitriles
3817
Imides to Esters or Lactones
3819
Imides to Amides
3820
Imides to Other Imides
3821
Nitriles to Esters
3822
Nitriles to Amides
3823
Other Interconversions
3826
MISCELLANEOUS REACTIONS
3831
Copyright

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Over de auteur (2018)

Richard C. Larock, PhD, is Professor Emeritus of Chemistry at Iowa State University. He is a pioneer in the use of palladium catalysts in organic synthesis, particularly in the synthesis of carbocycles and heterocycles. Dr. Larock has given over 420 research presentations and published about 350 articles, 32 patents, and 4 books including two editions of the bestselling classic Comprehensive Organic Transformations (Wiley 1996 and 1999).

Bibliografische gegevens