Immunobiology of the Head and Neck
This work reviews the basic concepts of immunology and introduces the reader to the latest findings on immunological aspects of diseases of the head and neck. In the past two decades, there has been an explosion of new knowledge in immunology. The contributors to this volume, all of whom have been active in clinical and basic research, describe how recent discoveries in immunology play an increasingly vital role in the understanding and care of patients with head and neck diseases. An important teaching tool for the resident in training and a valuable reference work for physicians in practice, this book will be of special interest to otolaryngologist-head and neck surgeons, surgical oncologists, pediatricians, allergists, rheumatologists and edu cators desiring an advanced text in the field. Jacques F. Poliquin, MD Allen F. Ryan, PhD Jeffrey P. Harris, MD, PhD INTRODUCTION Immunology has been traced back at least to 1000 AD. when the Chinese discovered that the inhalation of smallpox crusts had some value in prevention of the disease. However, immunology as a science has developed almost entirely within the last 100 years.
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Chapter 3Nonspecific immune response
Chapter 4Specific immune responses
Chapter 5Mucosal immune responses
Chapter 6Tonsillitis and adenoiditis
Chapter 8Nasal allergy
Chapter 9Hyperimmune and autoimmune diseases
Chapter 10Immunodeficiency diseases
Chapter 12Transplantation in otolaryngology
Chapter 13Clinical and Experimental Immunobiology of
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acid activity acute otitis media allergen allergic rhinitis Allergy Allergy Clin Immunol allograft anaphylatoxins anaphylaxis animals Ann Otol Rhinol antibody antibody response antigen antigenic determinants asthma autoimmune basophils cancer carcinoma cell≠mediated immunity cellular immunity chain chemotactic factors chronic Clin Allergy clinical complement components cytotoxic demonstrated disease effects enzymes eosinophils epithelium experimental function graft hapten head and neck histamine human hypersensitivity immune complexes immune response immune system immunogenic immunoglobulin immunologic immunotherapy induced infection inflammation inflammatory inhibition inner ear interaction involved leukocytes levels lymph nodes lymphocytes lymphoid tissue lymphokines macrophages mast cells mechanism mediators middle ear molecules mucosal nasal neutrophils nonspecific normal otitis media Otol Rhinol Laryngol Otolaryngol pathway patients plasma cells pollen production proteins ragweed reactions reactivity receptors release respiratory role secretions secretory sensitized serum skin testing specific studies substance suppressor surface syndrome T≠cell therapy tonsils transplantation treatment tumor tympanic membrane Veldman vitro