Applications of Liquid Scintillation Counting

Voorkant
Donald Horrocks
Elsevier, 2 dec. 2012 - 362 pagina's
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Applications of Liquid Scintillation Counting deals with liquid scintillation counting and its applications in fields such as the biosciences, medicine, environmental and space sciences, chemistry, and physics. These applications include dual-labeled counting; Cerenkov counting; radioimmunoassay, chemiluminescence and bioluminescence; pulse shape discrimination; flow cell counting; and large-volume counters.
This book is comprised of 18 chapters and begins with a historical overview of the liquid scintillation method, the first liquid scintillation counters, and early scintillator solutes. The following chapters focus on the theory of liquid scintillation counting; the components of the liquid scintillator solution; and the development of the liquid scintillation counter and multiplier phototubes. The discussion then turns to the detection and measurement of different types of particles produced by radionuclides using liquid scintillation techniques; the techniques and problems of sample preparations (homogeneous and heterogeneous); oxidation techniques; and importance and difference of several types of counting vials. The sources of quenching in counting samples and methods of monitoring and correction for variable quench within samples are also considered. Several special applications of liquid scintillation techniques are presented, including dual-labeled counting, radioimmunoassay, and flow cell counting. In conclusion, the statistical considerations involved in determining the reliability and accuracy of data obtained by nuclear counting techniques are highlighted.
This monograph will serve as a reliable source of information for those who are already using or starting to use liquid scintillation counting techniques.
 

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Inhoudsopgave

CHAPTER I INTRODUCTION
1
CHAPTER II BASIC PROCESSES
12
CHAPTER III SCINTILLATOR SOLUTIONS
35
CHAPTER IV LIQUID SCINTILLATION COUNTERS AND MULTIPLIER PHOTOTUBES
69
CHAPTER V PARTICLE COUNTING TECHNIQUES
90
CHAPTER VI PREPARATION OF COUNTING SAMPLES
145
CHAPTER VII OXIDATION TECHNIQUES
175
CHAPTER VIII COUNTING VIALS
188
CHAPTER XII CHEMILUMINESCENCE AND BIOLUMINESCENCE
238
CHAPTER XIII RADIOIMMUNOASSAY RIA
258
CHAPTER XIV CERENKOV COUNTING
263
CHAPTER XV PULSE SHAPE DISCRIMINATION
276
CHAPTER XVI FLOW CELL COUNTING
290
CHAPTER XVII LARGEVOLUME COUNTERS
298
CHAPTER XVIII STATISTICAL CONSIDERATIONS
306
AUTHOR INDEX
333

CHAPTER IX BACKGROUND
198
CHAPTER X QUENCH CORRECTION METHODS
208
CHAPTER XI DUALLABELED COUNTING
227

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